Given a DNA strand, return its RNA complement (per RNA transcription).
Both DNA and RNA strands are a sequence of nucleotides.
The four nucleotides found in DNA are adenine (A), cytosine (C), guanine (G) and thymine (T).
The four nucleotides found in RNA are adenine (A), cytosine (C), guanine (G) and uracil (U).
Given a DNA strand, its transcribed RNA strand is formed by replacing each nucleotide with its complement:
G
-> C
C
-> G
T
-> A
A
-> U
Go through the setup instructions for ECMAScript to install the necessary dependencies:
http://exercism.io/languages/ecmascript
Install assignment dependencies:
$ npm install
Execute the tests with:
$ npm test
In the test suites all tests but the first have been skipped.
Once you get a test passing, you can enable the next one by
changing xtest
to test
.
Hyperphysics http://hyperphysics.phy-astr.gsu.edu/hbase/Organic/transcription.html
It's possible to submit an incomplete solution so you can see how others have completed the exercise.
import Transcriptor from './rna-transcription';
describe('Transcriptor', () => {
const transcriptor = new Transcriptor();
test('empty rna sequence', () => {
expect(transcriptor.toRna('')).toEqual('');
});
xtest('transcribes cytosine to guanine', () => {
expect(transcriptor.toRna('C')).toEqual('G');
});
xtest('transcribes guanine to cytosine', () => {
expect(transcriptor.toRna('G')).toEqual('C');
});
xtest('transcribes adenine to uracil', () => {
expect(transcriptor.toRna('A')).toEqual('U');
});
xtest('transcribes thymine to adenine', () => {
expect(transcriptor.toRna('T')).toEqual('A');
});
xtest('transcribes all dna nucleotides to their rna complements', () => {
expect(transcriptor.toRna('ACGTGGTCTTAA'))
.toEqual('UGCACCAGAAUU');
});
xtest('correctly handles invalid input', () => {
expect(() => transcriptor.toRna('U')).toThrow(
new Error('Invalid input DNA.'),
);
});
xtest('correctly handles completely invalid input', () => {
expect(() => transcriptor.toRna('XXX')).toThrow(
new Error('Invalid input DNA.'),
);
});
xtest('correctly handles partially invalid input', () => {
expect(() => transcriptor.toRna('ACGTXXXCTTAA')).toThrow(
new Error('Invalid input DNA.'),
);
});
});
const notDna = /[^GCTA]/;
const dnaToRna = {
G: 'C',
C: 'G',
T: 'A',
A: 'U',
};
class Transcriptor {
toRna([...strand]) {
if (this.isNotADna(strand)) { throw new Error('Invalid input DNA.'); }
return strand.map(nucleotide => dnaToRna[nucleotide]).join('');
}
isNotADna(strand) {
return strand.join('').match(notDna);
}
}
export default Transcriptor;
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